Ethylene glycol used in car antifreeze is toxic because it is metabolized to oxalic acid, which is toxic. Acute shortterm exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects. Pure ethylene glycol has a specific heat capacity about one half that of water. However, ethylene glycol or solutions of ethylene glycol and water can form flammable vapors with air if heated sufficiently. Ethylene oxide reacts with water to produce ethylene glycol according to the chemical equation. Ethylene glycol can be recovered from the natural gas and reused as an inhibitor after purification treatment that removes water and inorganic salts. No data exposure controls personal protective equipment general protective and hygienic measures the usual precautionary measures for handling chemicals should be followed. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of. Wear positivepressure, selfcontained breathing apparatus scba and. The toxicity of eg via inhalation or skin contact is expected to be slight at room temperature. Prestone antifreezecoolant msdsp149 msds catalog service llc.
Ethylene glycol is oxidized to oxalic acid which results in the deposition of calcium oxalate crystals mainly in the brain and. Sds584 acdelco dexcool extended life antifreeze coolant date. Ethylene glycol industrialethylene glycol meglobalglycolsolv ethylene glycol, section 4. Gc extended life antifreeze coolant green cci part number canada 10439169 synonyms. For large fires, use alcohol type or allpurpose foams. It has many other names, including monoethylene glycol meg, 1,2ethanediol, and sometimes ethylene alcohol.
Acute oral ld50s 12,600 mgkg rat 23,700 mgkg mouse eye contact. Coolant uses advised against formation of mists or fog. Ethylene glycol material safety data sheet cas no 107. Es compleat coolant eg premix ethylene glycol based coolant msds nolt16587a msds revision date ddmmyyyy. The principal toxic effects of ethylene glycol, when swallowed. The atsdr toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here. Shellzone all season antifreezecoolant wbitterant page. The lethal dose in humans is estimated to be 100 ml 3 oz.
Firefighting measures suitable extinguishing media. Sds503 custom brand antifreezecoolant date prepared. Ethylene glycol material safety data sheet cas no 107211. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number chemtreco, inside the usa. Chronic, prolonged or repeated overexposure effects of repeated overexposure. Swallowing a small quantity of this material will result in serious health hazard. It is completely miscible with water and many organic liquids and depresses the freezing point when mixed with water. Ethylene glycol industrial ethylene glycol meglobal glycol solv ethylene glycol, section 4. Safety data sheet sds osha hazcom standard 29 cfr 1910. Please ensure that this msds is given to, and explained to people using this product.
It may be drunk accidentally or intentionally in an attempt to cause death. In a further study, comparing effects from high aerosol concentration by wholebody or noseonly exposure, it was shown that nose. This product contains ethylene glycol andor diethylene glycol which, if ingested, are. Identification product identifier es compleat coolant eg premix ethylene glycol based coolant. Safety data sheet mono ethylene glycol 1 identification of the substancepreparation and companyundertaking application automotive industry. Ethylene glycol 107211 hazard summary ethylene glycol has many uses, including as antifreeze in cooling and heating systems, in hydraulic brake fluids, and as a solvent. Safety data sheet lyden oil company lyden oil company. Fomepizole is easier to use clinically than ethanol, does not cause cns depression or hypoglycemia and requires less monitoring than ethanol. Ethylene glycol, commonly referred to as eg, is a chemical intermediate commonly found in antifreeze, refrigerants, and hydraulic fluids. The exposure limits that were valid when the msds was created were used. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet. Product name case powergard coolant synonyms inhibited ethylene glycol base antifreeze other means of identification not available relevant identified uses of the substance or mixture and uses advised against relevant identified uses ready to use corrosion inhibitor, engine coolant and antifreeze. The acute oral toxicities of the main components of this mixture are as follows. Ld 50 ethylene glycol 85 94 107211 diethylene glycol less than 5 111466.
Identification product name ethylene glycol cat no. Safety data sheet creation date 02feb2010 revision date 17jan2018 revision number 4 1. The lowest dose reported to produce death in humans was estimated to be 1,560 mgkg body weight. Hazards identification emergency overview appearance clear liquid with a mild odor may contain dye in one of several colors warning. Gc extended life antifreezecoolant green section iii health information inhalation. The end uses for ethylene glycol are numerous see table 1. Ethylene glycol is a colorless, odorless, sweet liquid, commonly found in antifreeze. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Ethylene glycol based antifreeze, precharged, fullyformulated extended life coolant. Central drug house p ltd 728 vardaan house new delhi2. Product identifier and chemical identity product identifier mono ethylene glycol other names ethylene glycol, glycol, meg, ethylene diol, 1,2ethanediol manufacturers product code 19950 recommended use radiator antifreeze coolant base fluid details of suppliermanufacturer. The combination of metabolic acidosis, an osmol gap and oxalate crystals in the urine is evidence of ethylene glycol poisoning. Additional therapeutic modalities which may decrease the adverse consequences of ethylene glycol. Material safety data sheet golden west global 5050.
The physical properties of ethylene glycolwater mixtures are therefore extremely important. Other pertinent literature is also presented, but is described in less detail. It can harm the eyes, skin, kidneys, and respiratory system. Ethylene glycol is produced from ethylene ethene, via the intermediate ethylene oxide. The signs and symptoms in ethylene glycol poisoning are those of metabolic. Typical applications would utilise a mixture of meg, technical water and a suitable wss corrosion inhibitor to meet the required freeze protection requirement.
The carbon dioxide comes in part from the ethylene oxide production, where a part of the ethylene is completely oxidized. Workers may be harmed from exposure to ethylene glycol. Relevant identified uses of the substance or mixture and uses advised against identified uses laboratory reagent. Ethylene glycol has not interfered with reproduction in animal studies except at very high doses. The currently recommended medical management of ethylene glycol poisoning includes elimination of ethylene glycol. Antifreeze ethylene glycol based concentrate nsn 6850006641409 and 6850006641403 41.
If necessary, dike well ahead of the spill to prevent runoff into drains, sewers, or any natural waterway or drinking supply. Ethylene glycol is a colorless, practically odorless, lowvolatility, lowviscosity, hygroscopic picks up water from the air liquid. Gc super extended life antifreezecoolant pink section iii health information inhalation. Mixture no single cas number applicable section ii ingredients hazardous ingredients % cas no. The administration of thiamine and pyridoxine is also recommended. Fleet charge 5050 prediluted antifreeze and coolant. The objective is to rapidly achieve and maintain a blood ethanol level of approximately 100 mgdl by giving a loading. Sds584 acdelco dexcool extended life antifreeze coolant date prepared. The diagnosis may be suspected when calcium oxalate crystals are seen in the urine or when acidosis or an. Once ingested, propylene glycol is either excreted in the urine or is metabolized to lactic acid, a normal metabolic product. Acute oral ld50s 4,700 mgkg rat 5,500 mgkg mouse 1,600 mgkg human diethylene glycol. Es compleat eg concentrate ethylene glycol based antifreeze msds nolt16588 msds revision date ddmmyyyy. For ethylene glycol poisoning, intravenous ethanol is a recognized antidotal treatment.
Pel mist pel vapor propylene glycol 57556 9496 none established none established. It is also used in hydraulic brake fluids and inks used in stamp pads, ballpoint pens, and print shops. Urinalysis may show albuminuria, hematuria and oxaluria. For small fires, use water spray, carbon dioxide or dry chemical. Recommended use of the chemical and restrictions on use. Mobil permazone antifreeze and coolant revision date. Excessive vapor concentrations of the major component ethylene glycol, as might be generated during heating of this material, have occasionally been. Ethylene glycol please ensure that this msds is given to, and explained to people using this product.
Ethylene glycol is used as antifreeze in cooling and heating systems, in hydraulic brake fluids, as an industrial humectant, as an ingredient of electrolytic condensers, as a solvent in the paint and plastics industries, in the formulations of printers inks, stamp pad inks, and inks for ballpoint pens, as a softening. Clinical chemistry may reveal aniongap metabolic acidosis and uremia. When broken down by the body it results in glycolic acid and oxalic acid which cause most of the toxicity. Material safety data sheet msds catalog service llc. Breathing excessive levels of the vapor or mist can irritate the respiratory tract. Product name antifreeze propylene glycol product number 2817 reach registration number 012119456809230000 cas number 57556 ec number 2003380 1. Ethylene glycol is oxidized to oxalic acid which results in the deposition of calcium oxalate crystals mainly in the. Repeated inhalation of ethylene glycol mist may produce signs of central nervous system involvement, particularly dizziness and nystagmus. The principal toxic effects of ethylene glycol, when swallowed, are kidney damage and metabolic acidosis. Fleet charge 5050 prediluted antifreeze and coolant safety data sheet according to federal register vol. This reaction can be catalyzed by either acids or bases, or can occur at neutral ph under elevated temperatures. Ethylene glycol monoethylene glycol 107211 95% water na 7732185 2. Pulmonary edema with hypoxemia has been described in.
Show this safety data sheet to the doctor in attendance. Pdf monoethyleneglycolproductspec90901823rdaug2017. Ethylene glycol is used to make antifreeze and deicing. Ethylene glycol is widely used to inhibit the formation of natural gas clathrates hydrates in long multiphase pipelines that convey natural gas from remote gas fields to a gas processing facility. Ethylene glycol is used as a protecting group in organic synthesis to protect carbonyl compounds such as ketones and aldehydes. Excessive vapor concentrations of the major component ethylene glycol, as might be generated during heating of this material, have occasionally been reported. The level of exposure depends upon the dose, duration, and work being done. Mono ethylene glycol 60100% casno 107211 ec no 2034733 classification 67548eec xn. Ethylene glycol is almost entirely used for industrial applications. Ethylene glycol is a synthetic liquid substance that absorbs. Chemical product and company identification product name.
192 1159 1127 269 1229 936 91 503 596 149 641 967 1229 1079 994 1216 39 869 180 793 1422 969 302 1558 1247 999 774 1545 1129 1191 1283 323 221 404 1420 1430 858 163 1455 893 1352 934